Poisonium is an asteroid material found in two of the "Safe Zone" sectors for your faction. It can be refined at the Factory and is used to build ships, weapons, and other items. This is one of the most difficult of the Safe Zone minerals to obtain, second only to Bluetonium. There are one level 3 and one level 4 poisonium sectors in each faction's safe zone. For Shards, the level 3 sector is Oberon, and the level 4 sector is Caldera. For Varians, the level 3 sector is Marak, and the level 4 sector is Gosh.